PLET-650

Product Introduction PLET-650
Propacetamol: Acetaminophen, also known as paracetamol, is commonly used for its analgesic and antipyretic effects. Its therapeutic effects are similar to salicylates, but it lacks anti-inflammatory, antiplatelet, and gastric ulcerative effects. Acetaminophen is metabolized primarily in the liver, where most of it is converted to inactive compounds by conjugation with glucuronic acid and, to a lesser extent, sulfuric acid. Conjugates are then excreted by the kidneys.

The toxic effects of acetaminophen are due to NAPQI, not acetaminophen itself nor any of the major metabolites. At therapeutic doses, NAPQI reacts with the sulfhydryl group of glutathione to produce a non-toxic conjugate that is excreted by the kidneys. High doses of acetaminophen may cause glutathione depletion, accumulation of NAPQI and hepatic necrosis

General Information:

Benefits of Medications:

1. Treating Conditions: Medications are primarily used to treat various medical conditions ranging from infections to chronic diseases.
2. Symptom Management: They can alleviate symptoms such as pain, inflammation, fever, etc.
3. Prevention: Some medications are used for prevention, such as vaccines or prophylactic antibiotics.
4. Improving Quality of Life: By managing symptoms and treating underlying conditions, medications can improve the quality of life for patients.

Indications (Conditions Treated):

• Paracetamol an analgesic and anti-pyretic. PLET- 500/650 is recommended for the treatment of painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea.

Side Effects

• Common side effects are Rash, itching/swelling (especially of the face/ tongue /throat), dizziness and trouble breath