CEPAROT-250

Benefit of FOSFOT
Fosfomycin
Fosfomycin is an old antibiotic agent. Fosfomycin is a molecule with a low molecular weight (MW) (138) . The molecular structure of fosfomycin differs in regard to the available drug formulations. Fosfomycin is a bactericidal antibiotic agent. It inhibits an enzyme-catalyzed reaction in the first step of the synthesis of the bacterial cell wall . Fosfomycin interferes with the first cytoplasmic step of bacterial cell wall biosynthesis, the formation of the peptidoglycan precursor UDP N-acetylmuramic acid (UDP-MurNAc) . Specifically, the enzyme UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is involved in peptidoglycan biosynthesis by catalyzing the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 3?-hydroxyl group of UDP-N-acetylglucosamine (UNAG).

Indication of FOSFOT
Fosfomycin is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering which is needed for their survival. It also reduces bacterial attachment to cells lining the bladder.
Side Effects Fosfomycin
Common side effects are Headache, Diarrhea, Inflammation of the nose